LHX3 antibody

Antigen: LHX3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN182573

Additional Information

Description: LHX3 is a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene. Keywords: LHX3,LIM homeobox 3,ARP32443_T100,NP_835258,NP_055379,NM_178138,NM_014564,Q9UBR4,DKFZp762A2013, M2-LHX3

Application Details

Application Notes: ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 2.5 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Research Area: Lineage Markers, Transcription Factors

Restrictions: For Research Use only

Images

anti-LHX3 antibody

Publications

Publications: Yaden, Garcia, Smith et al.: "Two promoters mediate transcription from the human LHX3 gene: involvement of nuclear factor I and specificity protein 1." in: Endocrinology, Vol. 147, Issue 1, pp. 324-37, 2005 (PubMed).