FOSB antibody (C-Term)

Catalog No. ABIN182594

The Rabbit Polyclonal anti-FOSB antibody has been validated for WB and IHC. It is suitable to detect FOSB in samples from Human, Mouse, Rat, Cow, Horse, Dog and Guinea Pig.

Quick Overview for FOSB antibody (C-Term) (ABIN182594)

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOSB Antibody

Binding Specificity: C-Term

Sequence: DLPGSAPAKE DGFSWLLPPP PPPPLPFQTS QDAPPNLTAS LFTHSEVQVL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FOSB. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOSB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: FOSB

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. They are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: AP-1, G0S3, GOS3, GOSB
Protein Interaction Partner: BAG3, SRA1, EP300, CREBBP, JUND, JUNB,
Protein Size: 338

Molecular Weight: 36 kDa

Gene ID: 2354

NCBI Accession: NM_006732, NP_006723

UniProt: P53539