Claudin 8 (CLDN8) (C-Term) antibody

Details for Product No. ABIN182852
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Antigen
Synonyms zgc:91900, wu:fa01e05, CLDN8, AI648025
Epitope
C-Term
(11), (7), (4), (3), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human
(26), (2), (1)
Host
Rabbit
(28), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(29), (15), (11), (4), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN182852
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Immunogen Synthetic peptide directed towards the C terminal of human CLDN8
Sequence IVGGALFCCV FCCNEKSSSY RYSIPSHRTT QKSYHTGKKS PSVYSRSQYV
Predicted Reactivity Human : 100 %, Bovine : 80 %
Characteristics This is a rabbit polyclonal antibody against CLDN8. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CLDN8
Background CLDN8, clustered with CLDN17 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
Molecular Weight 25 kDa
Gene ID 9073
NCBI Accession NM_199328, NP_955360
UniProt P56748
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 225 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Claudin 8 (CLDN8) (C-Term) antibody WB Suggested Anti-CLDN8 Antibody Titration: 0.5-1.0ug/ml
Positive Control: HepG2 cell lysate
anti-Claudin 8 (CLDN8) (C-Term) antibody (2) anti-Claudin 8 (CLDN8) (C-Term) antibody (Image 2)
anti-Claudin 8 (CLDN8) (C-Term) antibody (3) anti-Claudin 8 (CLDN8) (C-Term) antibody (Image 3)
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Validation Images
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