Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (N-Term) antibody

Details for Product No. ABIN182876
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Antigen
Synonyms ARTD17, PARP-6-B1, PARP-6-C, pART17, 1700119G14Rik, 2310028P13Rik, 3110038K10Rik, C030013N01Rik, PARP-6, RGD1310937
Epitope
N-Term
(14), (8), (5), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Zebrafish (Danio rerio), Human
(28), (7), (7), (5)
Host
Rabbit
(28)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(28), (11), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN182876
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PARP6
Sequence HINISFLDEE VSTAWKVLRT EPIVLRLRFS LSQYLDGPEP SIEVFQPSNK
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against PARP6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name PARP6
Background Poly(ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain. They are involved in DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.
Molecular Weight 59 kDa
Gene ID 56965
NCBI Accession NP_064599, NM_020214
UniProt Q9HAF3
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 519 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (N-Term) antibody WB Suggested Anti-PARP6 Antibody Titration: 1.25ug/ml
Positive Control: Daudi cell lysate
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Validation Images
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