Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (N-Term) antibody

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Antigen
Epitope
N-Term
(28), (16), (6), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(44), (10), (10), (8), (1), (1)
Host
Rabbit
(44)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(43), (20), (4), (3), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human PARP6
Sequence HINISFLDEE VSTAWKVLRT EPIVLRLRFS LSQYLDGPEP SIEVFQPSNK
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against PARP6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name PARP6
Background Poly(ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain. They are involved in DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.
Molecular Weight 59 kDa
Gene ID 56965
NCBI Accession NP_064599, NM_020214
UniProt Q9HAF3
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 519 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (N-Term) antibody (ABIN182876) WB Suggested Anti-PARP6 Antibody Titration: 1.25ug/ml
Positive Control: ...
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Catalog No. ABIN182876
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