CLIC2 antibody (Middle Region)

Catalog No. ABIN183128

The Rabbit Polyclonal anti-CLIC2 antibody is suitable to detect CLIC2 in samples from Human, Dog, Rat, Guinea Pig, Horse, Rabbit and Cow. It has been validated for WB.

Quick Overview for CLIC2 antibody (Middle Region) (ABIN183128)

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Reactivity: Human, Dog, Rat, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLIC2 Antibody

Binding Specificity: Middle Region

Sequence: HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLIC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 247 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLIC2

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Alternative Name: CLIC2

Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 2 (CLIon Channel2) is a member of the p64 family, the protein is detected in fetal liver and adult skeletal muscle tissue.
Alias Symbols: CLIC2b, XAP121
Protein Interaction Partner: UBC, FN1, NEDD4L, NEDD4, TRAPPC2,
Protein Size: 247

Molecular Weight: 27 kDa

Gene ID: 1193

NCBI Accession: NM_001289, NP_001280

UniProt: O15247

Pathways: Negative Regulation of Transporter Activity