NRIP2 antibody (N-Term)

Catalog No. ABIN183472

Product Details anti-NRIP2 Antibody

Target: NRIP2 (Nuclear Receptor Interacting Protein 2 (NRIP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HLSQQRQLKQ ATQFLHKDSA DLLPLDSLKR LGTSKDLQPH SVIQRRLVEG

Predicted Reactivity: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against NRIP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse NRIP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 229 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NRIP2

Target: NRIP2 (Nuclear Receptor Interacting Protein 2 (NRIP2))

Alternative Name: NRIP2 (NRIP2 Products)

Background: NIX1 holds two copies of the LXXLL motif. NIX1 displays a neuronal specific expression pattern. It selectively interacts with distinct nuclear receptors of the RAR and TR subfamily, but does not bind steroid hormone receptors. By docking to activated nuclear receptors in an AF2-D-dependent fashion, NIX1 might displace coactivators and result in suppression of the transcriptional activity of liganded nuclear receptors.
Alias Symbols: NIX1, AW491344
Protein Interaction Partner: Rorb, Thrb, Rara,
Protein Size: 229

Molecular Weight: 25 kDa

Gene ID: 60345

NCBI Accession: NM_021717, NP_068363

UniProt: Q14BZ2