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YAF2 antibody

Antigen

YAF2
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine), Rat (Rattus)
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN183479
Quantity 50 µg  (Variants)
Price Product not available in this region.
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anti-YAF2 antibody

Additional Information
Application Details Publications Images Alternatives Secondary Antibodies Variants back to top

Description Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling. Keywords: YAF2, ARP37341_P050, NP_077151, NM_024189, Q99LW6, 2810021M11Rik

Application Details
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Application Notes ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 0.2 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Restrictions For Research Use only

Publications
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Publications Kaneko, Miyagishima, Hasegawa et al.: "The mouse YAF2 gene generates two distinct transcripts and is expressed in pre-and postimplantation embryos." in: Gene, Vol. 315, pp. 183-92, 2003 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies Variants back to top

Alternatives for antigen "YAF2", type "Antibodies"
Hosts Rabbit (2), Mouse (1)
Reactivities Human (2), Mouse (Murine) (1)
Applications Western Blotting (WB) (3), ELISA (Detection) (1), Immunohistochemistry (IHC) (1)