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Transcription Factor EB (TFEB) antibody

Antigen

Transcription Factor EB (TFEB)
Synonyms TCFEB, bHLHe35, AlphaTFEB, TFEB, Tcfeb, MGC116240, tcfeb, MGC145796, alphatfeb
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit, Chicken, Zebrafish, Pig (Porcine), Xenopus laevis
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN183717
Quantity 0.1 mg  (Variants)
Price 251.90 $   Plus shipping costs $45.00
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anti-Transcription Factor EB (TFEB) antibody

Additional Information
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Alternative name TFEB
Gene ID TFEB
UniProt P19484
Immunogen The immunogen for anti-TFEB antibody: synthetic peptide directed towards the C terminal of human TFEB
Sequence SLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRS SFSMEEGDVL
Cross-Reactivity Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
Format Lyophilized
Reconstitution Add 100 µl of distilled water. Final anti-TFEB antibody concentration is 1 mg/ml.
Description TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t(6,11)(p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Characteristics Antigen Size: 476 amino acids
Molecular Weight 53kDa

Application Details
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Application Notes WB Suggested Anti-TFEB Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Purification Protein A purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only

Publications
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Product Argani, Laé, Hutchinson et al.: "Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR." in: The American journal of surgical pathology, Vol. 29, Issue 2, pp. 230-40, 2005 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Transcription Factor EB (TFEB)", type "Antibodies"
Hosts Rabbit (38), Goat (9), Mouse (5)
Reactivities Human (45), Mouse (Murine) (25), Rat (Rattus) (23), Dog (Canine) (20), Cow (Bovine) (19), Horse (Equine) (18), Pig (Porcine) (18), Chicken (1), Rabbit (1)
Applications Western Blotting (WB) (27), ELISA (23), Immunofluorescence (IF) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Chromatin Immunoprecipitation (ChiP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (IHC) (2), Dot Blot (Dot) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (7), Internal Region (5), AA 220-238 (1), AA 285-300 (1), AA 87-103 (1), C-Term (1), Center (1)