KHDRBS3 antibody (C-Term)

Catalog No. ABIN184009

Product Details anti-KHDRBS3 Antibody

Target: KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EQSYDSYDNS YSTPAQSGAD YYDYGHGLSE ETYDSYGQEE WTNSRHKAPS

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KHDRBS3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 346 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KHDRBS3

Target: KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))

Alternative Name: KHDRBS3 (KHDRBS3 Products)

Background: As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
Alias Symbols: Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile
Protein Interaction Partner: YTHDC1, DMRT3, MARK4, NCOA5, PRPF31, BAHD1, KHDRBS3, INPP5D, UBC, BMI1, NELFB, RBM7, PSMF1, SIAH1, HNRNPK, KHDRBS2, CCDC33, PTBP2, U2AF2, KHDRBS1, SNRPC, HNRNPC, FUS, FBXO32, SERPINB5, RBBP6, CACNA1A, RPAP2, ZNF408, LNX1, SGSM2, SRSF9, NUDT18, PRMT1, RBMY
Protein Size: 346

Molecular Weight: 38 kDa

Gene ID: 10656

NCBI Accession: NM_006558, NP_006549

UniProt: O75525