EXOSC4 antibody (N-Term)

Catalog No. ABIN184050

This anti-EXOSC4 antibody is a Rabbit Polyclonal antibody detecting EXOSC4 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for EXOSC4 antibody (N-Term) (ABIN184050)

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EXOSC4 Antibody

Binding Specificity: N-Term

Sequence: SDQGYRVDGR RAGELRKIQA RMGVFAQADG SAYIEQGNTK ALAVVYGPHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 245 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC4

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Alternative Name: EXOSC4

Background: EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.
Alias Symbols: SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p
Protein Interaction Partner: EED, TOM1, NMI, H1FX, HIST1H1E, TSEN15, GADD45GIP1, FAHD1, SMPD4, LRRC8D, EXOSC1, EXOSC3, MPZL1, SKIV2L, EXOSC10, EXOSC9, NEK1, HNRNPD, DXO, AICDA, UBC, ESR2, EXOSC5, DDX47, EXOSC2, EXOSC7, EXOSC8, PSIP1, EXOSC6, DIS3L, EXOSC4, SKIV2L2, DIS3, UPF2, MPP6,
Protein Size: 245

Molecular Weight: 27 kDa

Gene ID: 54512

NCBI Accession: NM_019037, NP_061910

UniProt: Q9NPD3