EXOSC4 antibody (N-Term)

Catalog No. ABIN2779148

The Rabbit Polyclonal anti-EXOSC4 antibody (ABIN2779148) specifically detects EXOSC4 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for EXOSC4 antibody (N-Term) (ABIN2779148)

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EXOSC4 Antibody

Binding Specificity: N-Term

Purpose: EXOSC4 Antibody - N-terminal region

Sequence: SDQGYRVDGR RAGELRKIQA RMGVFAQADG SAYIEQGNTK ALAVVYGPHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100081

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC4

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Alternative Name: EXOSC4

Background:

Background Information: EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.

Gene Name: Exosome component 4

Alternative Symbols: SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p

Protein Name: Exosome complex component RRP41

Molecular Weight: 27kDa

Gene ID: 54512

NCBI Accession: NP_061910

UniProt: Q9NPD3