HNRNPA3 antibody (N-Term)

Catalog No. ABIN184093

This Rabbit Polyclonal antibody specifically detects HNRNPA3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit and Cow and has been mentioned in 3+ publications.

Quick Overview for HNRNPA3 antibody (N-Term) (ABIN184093)

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HNRNPA3 Antibody

Binding Specificity: N-Term

Sequence: MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HNRPA3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 378 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HNRNPA3 antibody (ABIN184093)

Papadopoulou, Patrinou-Georgoula, Guialis: "Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes." in: Biochimica et biophysica acta, Vol. 1804, Issue 4, pp. 692-703, (2010) (PubMed).

Süss, Czupalla, Winter, Pursche, Knoch, Schroeder, Hoflack, Solimena: "Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 3, pp. 393-408, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for HNRNPA3

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Alternative Name: HNRPA3

Background: HNRPA3 plays a role in cytoplasmic trafficking of RNA. It binds to the cis-acting response element(A2RE) and may be involved in pre-mRNA splicing
Alias Symbols: FBRNP, HNRPA3, D10S102, 2610510D13Rik
Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, LIN28A, SUMO1, NEDD8, MDM2, RPA3, RPA2, RPA1, WWOX, ZBTB1, RNF2, EED, rev, PARK2, TARDBP, IGSF8, ICAM1, CD81, PAN2, TP63, WHSC1, VCAM1, ITGA4, IL7R, IFIT3, FN1, ESR1, SMURF1, YWHAE, RPS28, RPS13, RPLP2, RAB1A, PTBP1, HSPA8, HSPA5
Protein Size: 378

Molecular Weight: 42 kDa

Gene ID: 220988

NCBI Accession: NM_194247, NP_919223

UniProt: P51991