HNRNPA3 antibody (N-Term)

Catalog No. ABIN2776678

This Rabbit Polyclonal antibody specifically detects HNRNPA3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit and Cow. It has been mentioned in 3+ publications

Quick Overview for HNRNPA3 antibody (N-Term) (ABIN2776678)

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HNRNPA3 Antibody

Binding Specificity: N-Term

Purpose: HNRPA3 Antibody - N-terminal region

Sequence: MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HNRPA3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102433

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-HNRNPA3 antibody (ABIN2776678)

Papadopoulou, Patrinou-Georgoula, Guialis: "Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes." in: Biochimica et biophysica acta, Vol. 1804, Issue 4, pp. 692-703, (2010) (PubMed).

Süss, Czupalla, Winter, Pursche, Knoch, Schroeder, Hoflack, Solimena: "Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 3, pp. 393-408, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for HNRNPA3

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Alternative Name: HNRPA3

Background:

Background Information: HNRPA3 plays a role in cytoplasmic trafficking of RNA. It binds to the cis-acting response element(A2RE) and may be involved in pre-mRNA splicing

Gene Name: Heterogeneous nuclear ribonucleoprotein A3

Alternative Symbols: FBRNP, HNRPA3, D10S102, 2610510D13Rik

Protein Name: Heterogeneous nuclear ribonucleoprotein A3

Molecular Weight: 42kDa

Gene ID: 220988

NCBI Accession: NP_919223

UniProt: P51991