NrCAM antibody (AA 1192-1255)

Catalog No. ABIN1843141

This Mouse Monoclonal antibody specifically detects NrCAM in WB, ELISA and IF/ICC. It exhibits reactivity toward Human.

Quick Overview for NrCAM antibody (AA 1192-1255) (ABIN1843141)

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NrCAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-NrCAM Antibody

Binding Specificity: AA 1192-1255

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for NrCAM

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Alternative Name: NRCAM

Background: Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily.This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains.This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth.This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration.Allelic variants of this gene have been associated with autism and addiction vulnerability.Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 144 kDa

Gene ID: 4897

UniProt: Q92823

Pathways: Regulation of Cell Size