Interferon Regulatory Factor 8 (IRF8) antibody
| Antigen |
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| Synonyms |
ICSBP, IRF-8, ICSBP1, H-ICSBP, Myls, Icsbp1, AI893568, IRF8, zgc:92252, icsbp1, MGC80112, MGC140338, DKFZp469B0320 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Zebrafish, Chicken, Xenopus laevis
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
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| Catalog no. |
ABIN184318 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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IRF8 / ICSBP1
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Gene ID
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IRF8
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UniProt
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Q02556
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Immunogen
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The immunogen for anti-IRF8 antibody: synthetic peptide directed towards the N terminal of human IRF8
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Sequence
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MFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAE PATWKTRLRC
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-IRF8 antibody concentration is 1 mg/ml.
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Description
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Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
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Characteristics
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Antigen Size: 426 amino acids
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Molecular Weight
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48kDa
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Application Notes
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WB Suggested Anti-IRF8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Weisz, Marx, Sharf et al.: "Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes." in: The Journal of biological chemistry, Vol. 267, Issue 35, pp. 25589-96, 1993 (PubMed).
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Alternatives for antigen "Interferon Regulatory Factor 8 (IRF8)", type "Antibodies"
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Hosts
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Rabbit (30), Goat (5)
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Reactivities
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Human (31), Mouse (Murine) (13), Rat (Rattus) (9), Cow (Bovine) (3), Dog (Canine) (3), Chicken (2), Cat (Feline) (1), Xenopus laevis (1), Zebrafish (1)
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Applications
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Western Blotting (WB) (33), ELISA (19), Immunohistochemistry (IHC) (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Dot Blot (DB) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
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Epitopes
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C-Term (12), Internal Region (2), N-Term (2), Center (1)
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