Protein SET (SET) antibody

Antigen: Protein SET (SET)

Synonyms: 2PP2A, IGAAD, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETA, AA407739, StF-IT-1, MGC118419, 2610030F17Rik, 5730420M11Rik, Ab1-115

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184618

Additional Information

Alternative name: SET / I2 alpha PP2A

Gene ID: 6418

Immunogen: SAPAAKVSKKELNS-C

Format: Affinity-purified

Description: All names and symbols: SET, SET nuclear oncogene, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA, LA-DR-associated protein II, OTTHUMP00000022286, SET translocation (myeloid leukemia-associated), Template-Activating Factor-I, chromatin remodelling factor, inhibitor of granzyme A-activated DNase, inhibitor-2 of protein phosphatase-2A, protein phosphatase type 2A inhibitor, template-activating factor I. Official Symbol: SET. RefSeq number(s): NP_003002.2. Gene ontology terms: protein phosphatase inhibitor activity, DNA replication factor, nucleosome assembly, DNA replication, oncogenesis, nucleus

Specificity: This antibody is expected to recognize isoform 2 (NP_003002.2). Human, Cow

Application Details

Application Notes: Western blot: Approx 20-25kDa and 40kDa bands seen in Human Kidney extracts. Recommended for use at 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184618 staining (2µg/ml) of Human Kidney extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Ozbun, You, Kiang et al.: "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily." in: Genomics, Vol. 73, Issue 2, pp. 179-93, 2001 (PubMed).