Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) antibody

Antigen: Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2)

Synonyms: MGC10562, MGC37615, FRAT2

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184718

Additional Information

Alternative name: FRAT2 / GSK-3

Gene ID: 23401

Immunogen: C-GPDRIALQPSGSLL

Format: Affinity-purified

Description: All names and symbols: FRAT2, GSK-3, frequently rearranged in advanced T-cell lymphomas 2, GSK-3 binding protein FRAT2. Official Symbol: FRAT2. RefSeq number(s): NP_036215.1. Gene ontology terms: molecular_function unknown, development, cell proliferation, cellular_component unknown

Specificity: Human 233 aa

Application Details

Application Notes: Western blot: Approx 30-35kDa band seen in Human Heart lysate. Recommended for use at 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184718 staining (2µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Saitoh, Moriwaki, Koike et al.: "Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway." in: Biochemical and biophysical research communications, Vol. 281, Issue 3, pp. 815-20, 2001 (PubMed).