Interferon Regulatory Factor 6 (IRF6) antibody

Antigen: Interferon Regulatory Factor 6 (IRF6)

Synonyms: LPS, PIT, PPS, VWS, OFC6, mirf6, AI876454, E230028I05Rik, MGC63500, zgc:63500, IRF6, xIRF-6, MGC81304, lps, pit, pps, vws, ofc6, MGC143192, DKFZp469E012

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184730

Additional Information

Alternative name: IRF6

Gene ID: 3664, 54139 (mouse)

Immunogen: C-TPSMQLPPALPPQ

Description: All names and symbols: IRF6, interferon regulatory factor 6, LPS, PIT, PPS, VWS. Official Symbol: IRF6. RefSeq number(s): NP_006138. Gene ontology terms: transcription factor activity, regulation of transcription, DNA-dependent, nucleus

Specificity: Human, Mouse

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution >1/32,000. Western Blot: Approx 60kDa band observed in Human Ovary lysate (predicted MW of 58kDa according to NP_006138). Recommended for use at 0.2-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Chromatin and Nuclear Signaling, Transcription Factors, Innate Immunity, Cytokines

Restrictions: For Research Use only

Images

ABIN184730 staining (0.2µg/ml) of Human Ovary lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Kondo, Schutte, Richardson et al.: "Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes." in: Nature genetics, Vol. 32, Issue 2, pp. 285-9, 2002 (PubMed).