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Caspase Recruitment Domain Family, Member 6 (CARD6) antibody

Antigen

Caspase Recruitment Domain Family, Member 6 (CARD6)
Synonyms CINCIN1, D730008L15, CARD6
Clonality Polyclonal
Host
Reactivity
Alternatives

Human
Application
Alternatives ELISA, Immunohistochemistry (IHC)
1 reference available
Catalog no. ABIN184977
Quantity 100 ug
Price 501.80 $   Plus shipping costs $35.00
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anti-Caspase Recruitment Domain Family, Member 6 (CARD6) antibody

Additional Information
Application Details Publications Images Alternatives Secondary Antibodies back to top

Alternative name CARD6
Gene ID 84674
Immunogen ATESTPSEIIERER-C
Format Affinity-purified
Description All names and symbols: CARD6, caspase recruitment domain family, member 6, caspase recruitment domain protein 6. Official Symbol: CARD6. RefSeq number(s): NP_115976. Gene ontology terms: apoptosis, intracellular, apoptosis regulator activity
Specificity Human

Application Details
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Application Notes Peptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Approx. 45-50kDa and 25-30kDa bands observed in A549, Human Heart and Human Skeletal Muscle lysates at 1ug of primary. Please note that the bands we observe are different from the predicted size of approx. 119kDa according to NP_115976. Currently we cannot find an explanation for this in the literature. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any splice variants/modified forms been reported? Immunohistochemistry: In paraffin embedded Human Pancreas shows variable staining of cytoplasm in acinar cells. Recommended concentration, 5-10µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Apoptosis/Necrosis
Restrictions For Research Use only

Publications
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Publications Stehlik, Hayashi, Pio et al.: "CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31941-9, 2003 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies back to top

Alternatives for antigen "Caspase Recruitment Domain Family, Member 6 (CARD6)", type "Antibodies"
Hosts Rabbit (25), Goat (4), Mouse (1)
Reactivities Human (29)
Applications Flow Cytometry (FACS) (16), Immunofluorescence (IF) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Western Blotting (WB) (6), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunoprecipitation (IP) (4), ELISA (3), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (2)