alpha-1-Syntrophin (SNTA1) antibody

Antigen: alpha-1-Syntrophin (SNTA1)

Synonyms: SNT1, LQT12, TACIP1, dJ1187J4.5

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185131

Additional Information

Alternative name: Syntrophin (alpha 1)

Gene ID: 6640, 20648 (mouse)

Immunogen: ASGRRAPRTGLLE-C

Format: Affinity-purified

Description: All names and symbols: syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), SNTA1, SNT1, TACIP1, dJ1187J4.5, pro-TGF-alpha cytoplasmic domain-interacting protein 1, dystrophin-associated protein A1, 59kD, acidic component, syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component). Official Symbol: SNTA1. RefSeq number(s): NP_003089.1. Gene ontology terms: actin binding, calmodulin binding, calcium ion binding, muscle contraction, membrane, cytoskeleton

Specificity: Human, Mouse, Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 60kDa band observed in Human Skeletal Muscle lysates (calculated MW of 53.9kDa according to NP_003089.1). Recommended concentration: 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185131 (0.01µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Fernandez-Larrea, Merlos-Suarez, Urena et al.: "A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface." in: Molecular cell, Vol. 3, Issue 4, pp. 423-33, 1999 (PubMed).