Hermansky-Pudlak Syndrome 3 (HPS3) antibody

Antigen: Hermansky-Pudlak Syndrome 3 (HPS3)

Synonyms: SUTAL, FLJ22704, DKFZp686F0413, HPS3

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185260

Additional Information

Alternative name: HPS3 / Cocoa

Gene ID: 84343

Immunogen: PYLLYCSRKKPLT

Description: All names and symbols: HPS3, SUTAL, FLJ22704, Hermansky-Pudlak syndrome 3, cocoa,. Official Symbol: HPS3. RefSeq number(s): NP_115759

Specificity: Human 1004 aa

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Approx 110kDa band observed in A431 cell lysate (calculated MW of 114kDa according to NP_115759). Recommended concentration: 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185260 (1µg/ml) staining of A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Gautam, Chintala, Li et al.: "The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2)." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12935-42, 2004 (PubMed).