Formin Binding Protein 1 (FNBP1) antibody

Antigen: Formin Binding Protein 1 (FNBP1)

Synonyms: FBP17, KIAA0554, MGC126804, FBP1, Fbp17, 1110057E06Rik, 2210010H06Rik, MGC80847, MGC122623, MGC146466

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185286

Additional Information

Alternative name: FBP17 / FNBP1

Gene ID: 23048

Immunogen: KQLESSKRRFERDC

Description: All names and symbols: FNBP1, FBP17, KIAA0554, formin binding protein 1, formin-binding protein 17, MGC126804. Official Symbol: FNBP1. RefSeq number(s): NP_055848.1

Specificity: Human, Mouse, Rat 617 aa

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 70kDa band observed in human testis lysates (calculated MW of 71.3kDa according to NP_055848.1). Recommended concentration: 0.25-2µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185286 staining (0.25µg/ml) of human testis lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Fuchs, Rehkamp, Haas et al.: "The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 15, pp. 8756-61, 2001 (PubMed).

Kamioka, Fukuhara, Sawa et al.: "A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 40091-9, 2004 (PubMed).