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CCK-A Receptor (CCKAR) antibody

Antigen

CCK-A Receptor (CCKAR)

Synonyms CCK-A, CCKRA, CCK1-R
Clonality Polyclonal
Host
Reactivity
Alternatives

Human

Application
Alternatives ELISA, Immunohistochemistry (IHC)
2 references available
Catalog no. ABIN185408
Quantity 100 ug
Price 501.80 $   Plus shipping costs $35.00
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Additional Information

Alternative name CCKAR
Gene ID 886, 12425 (mouse), 24889 (rat)
Immunogen C-FEASQKKSAKERKPST
Format Affinity-purified
Description All names and symbols: CCKAR, cholecystokinin A receptor , HGNC:1570, CCK-A, CCK1-R. Official Symbol: CCKAR. RefSeq number(s): NP_000721.1
Specificity Human 428 aa

Application Details

Application Notes Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Preliminary experiments in Human Pancreas lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). Immunohistochemistry: In paraffin embedded Human Pancreas, shows cytoplasmic staining of some cells in the islets of Langerhans. Recommended concentration, 10µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Neurology, Alzheimer's Disease
Restrictions For Research Use only

Publications

Publications Beglinger, Degen, Matzinger et al.: "Loxiglumide, a CCK-A receptor antagonist, stimulates calorie intake and hunger feelings in humans." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 280, Issue 4, pp. R1149-54, 2001 (PubMed).

Varga, Balint, Burghardt et al.: "Involvement of endogenous CCK and CCK1 receptors in colonic motor function." in: British journal of pharmacology, Vol. 141, Issue 8, pp. 1275-84, 2004 (PubMed).

Alternatives

Alternatives for antigen "CCK-A Receptor (CCKAR)", type "Antibodies"
Hosts Rabbit (13), Goat (6), Mouse (1)
Reactivities Human (13), Rat (Rattus) (7), Mouse (Murine) (6), Rabbit (1)
Applications Western Blotting (WB) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Enzyme Immunoassay (EIA) (4), Immunofluorescence (IF) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (1), Flow Cytometry (FACS) (1), Immunohistochemistry (IHC) (1)
Epitopes AA 197-210 (3), AA 180-195 (2), N-Term (1)