SH2 Domain Containing 1A (SH2D1A) antibody

Antigen: SH2 Domain Containing 1A (SH2D1A)

Synonyms: LYP, SAP, XLP, DSHP, EBVS, IMD5, XLPD, MTCP1, FLJ18687, FLJ92177

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185426

Additional Information

Alternative name: SH2D1A / SAP

Gene ID: 4068

Immunogen: C-HKRYFRKIKN

Format: Affinity-purified

Description: All names and symbols: SH2D1A, SAP, SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome), HGNC:10820, DSHP, EBVS, IMD5, LYP, MTCP1, XLP, XLPD , SH2 domain protein 1A, SLAM (signaling lymphocyte activation molecule) associated protein. Official Symbol: SH2D1A. RefSeq number(s): NP_002342.1

Specificity: Human, Mouse, Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 16kDa band observed in Human Thymus lysates (calculated MW of 14.2kDa according to NP_002342.1). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185426 staining (0.3µg/ml) of Human Thymus lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Mikhalap, Shlapatska, Yurchenko et al.: "The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells." in: Blood, Vol. 104, Issue 13, pp. 4063-70, 2004 (PubMed).