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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (C-Term) antibody

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Antigen
Synonyms IP, PGL4, SDH, SDH1, SDH2, SDHIP, 0710008N11Rik, Ip, MGC53699, MGC130803, fj46d06, MGC165456, wu:fj46d06
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type

Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN185447
Quantity 100 ug
Price
374.27 $   Plus shipping costs $45.00
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anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (C-Term) antibody

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen Peptide with sequence C-ATYKEKKASV, from the C Terminus of the protein sequence according to NP_002991.2.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name SDHB
Background Synonyms: SDHB, IP, SDH, SDH1, SDHIP, succinate dehydrogenase complex, subunit B, iron sulfur (Ip), OTTHUMP00000044624, iron-sulfur subunit, FLJ92337, SDH2, SDHIP
Gene ID 6390
NCBI Accession NP_002991.2
Research Area Metabolism

Application Details

Target Details Handling Images References Alternatives back to top
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Approx 28 kDa band observed in Human Liver lysates (calculated MW of 31.6 kDa according to NP_002991.1). Recommended concentration: 0.03-0.1 µg/mL. ELISA: Customer successfully used this product in quantitative ELISA on HepG2 lysates.
Restrictions For Research Use only

Handling

Target Details Application Details Images References Alternatives back to top
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.

References

Target Details Application Details Handling Images Alternatives back to top
Morris, Maina, Morgan et al.: "Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma." in: Journal of clinical pathology, Vol. 57, Issue 7, pp. 706-11, 2004 (PubMed).

Selak, Armour, MacKenzie et al.: "Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase." in: Cancer cell, Vol. 7, Issue 1, pp. 77-85, 2005 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB)", type "Antibodies"
Hosts (28), (4)
Reactivities (30), (21), (20), (18), (18), (18), (17), (1), (1), (1), (1)
Applications (17), (16), (11), (6), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (2), (1), (1), (1)
Beacon
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