SDHB antibody (AA 29-280)
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- Target See all SDHB Antibodies
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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Binding Specificity
- AA 29-280
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SDHB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- AQTAAATAPR IKKFAIYRWD PDKAGDKPHM QTYEVDLNKC GPMVLDALIK IKNEVDSTLT FRRSCREGIC GSCAMNINGG NTLACTRRID TNLNKVSKIY PLPHMYVIKD LVPDLSNFYA QYKSIEPYLK KKDESQEGKQ QYLQSIEERE KLDGLYECIL CACCSTSCPS YWWNGDKYLG PAVLMQAYRW MIDSRDDFTE ERLAKLQDPF SLYRCHTIMN CTRTCPKGLN PGKAIAEIKK MMATYKEKKA SV
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 29-280 of human SDHB (NP_002991.2).
- Isotype
- IgG
- Top Product
- Discover our top product SDHB Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- Alternative Name
- SDHB (SDHB Products)
- Synonyms
- succinate dehydrogenase 2-3 antibody, CG3283 antibody, Dmel\\CG3283 antibody, Ip antibody, SDH antibody, SDH-IP antibody, SDH-Ip antibody, SDHb antibody, sdhB antibody, CWS2 antibody, IP antibody, PGL4 antibody, SDH1 antibody, SDH2 antibody, SDHIP antibody, 0710008N11Rik antibody, fj46d06 antibody, wu:fj46d06 antibody, succinate dehydrogenase complex iron sulfur subunit B antibody, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antibody, Succinate dehydrogenase, subunit B (iron-sulfur) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antibody, SDHB antibody, SDH2-3 antibody, SdhB antibody, sdhb antibody, Sdhb antibody, sdhb.S antibody
- Background
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.,SDHB,CWS2,IP,PGL4,SDH,SDH1,SDH2,SDHIP,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,SDHB
- Molecular Weight
- 31 kDa
- Gene ID
- 6390
- UniProt
- P21912
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