SDHB antibody (AA 29-280)

Catalog No. ABIN7193552

Product Details anti-SDHB Antibody

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Binding Specificity: AA 29-280

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SDHB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human SDHB (AA: 29-280) expressed in E. coli.

Clone: 2B2B1

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for SDHB

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Alternative Name: SDHB (SDHB Products)

Synonyms: succinate dehydrogenase 2-3 antibody, CG3283 antibody, Dmel\\CG3283 antibody, Ip antibody, SDH antibody, SDH-IP antibody, SDH-Ip antibody, SDHb antibody, sdhB antibody, CWS2 antibody, IP antibody, PGL4 antibody, SDH1 antibody, SDH2 antibody, SDHIP antibody, 0710008N11Rik antibody, fj46d06 antibody, wu:fj46d06 antibody, succinate dehydrogenase complex iron sulfur subunit B antibody, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antibody, Succinate dehydrogenase, subunit B (iron-sulfur) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antibody, SDHB antibody, SDH2-3 antibody, SdhB antibody, sdhb antibody, Sdhb antibody, sdhb.S antibody

Background:

Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Aliases: IP, SDH, CWS2, PGL4, SDH1, SDH2, SDHIP

Molecular Weight: 31.6 kDa

Gene ID: 6390