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Synaptic Vesicle Glycoprotein 2A (SV2A) antibody

Antigen

Synaptic Vesicle Glycoprotein 2A (SV2A)

Synonyms SV2, KIAA0736, AI746429, mKIAA0736, Sv2, MGC105346, SV2A, DKFZp459I223
Clonality Polyclonal
Host
Reactivity
Alternatives

Rat (Rattus)

Application
Alternatives ELISA, Western Blotting (WB)
1 reference available
Catalog no. ABIN185715
Quantity 100 ug
Price 501.80 $   Plus shipping costs $35.00
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Additional Information

Alternative name SV2A
Gene ID 9900, 64051 (mouse), 117559 (rat)
Immunogen C-TVELYPSDKRTTA
Format Affinity-purified
Description All names and symbols: SV2A, synaptic vesicle glycoprotein 2A, KIAA0736, SV2 , synaptic vesicle glycoprotein 2. Official Symbol: SV2A. RefSeq number(s): NP_055664.2
Specificity Human, Mouse, Rat, Dog 742 aa

Application Details

Application Notes Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 80kDa band observed in rat brain lysates (calculated MW of 82.6kDa according to NP_476558.1 (rat)). Recommended concentration: 0.3-1µg/ml. An additonal band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunising peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Neurology
Restrictions For Research Use only

Publications

Publications Dong, Yeh, Tepp et al.: "SV2 is the protein receptor for botulinum neurotoxin A." in: Science (New York, N.Y.), Vol. 312, Issue 5773, pp. 592-6, 2006 (PubMed).

Alternatives

Alternatives for antigen "Synaptic Vesicle Glycoprotein 2A (SV2A)", type "Antibodies"
Hosts Rabbit (23), Goat (3), Mouse (1)
Reactivities Human (23), Cow (Bovine) (17), Dog (Canine) (17), Mouse (Murine) (17), Rat (Rattus) (17), Pig (Porcine) (16), Rabbit (16), Horse (Equine) (15), Sheep (Ovine) (1)
Applications Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (9), ELISA (4), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (1)