Filamin B, beta (FLNB) antibody

Antigen: Filamin B, beta (FLNB)

Synonyms: AOI, FH1, SCT, TAP, LRS1, TABP, FLN1L, ABP-278, ABP-280, DKFZp686O033, DKFZp686A1668, FLNB

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN185734

Additional Information

Alternative name: FLNB

Gene ID: 2317, 286940 (mouse), 306204 (rat)

Immunogen: KITDDSRRCSQVK

Format: Affinity-purified

Description: All names and symbols: FLNB, filamin B, beta (actin binding protein 278) , ABP-278, AOI, DKFZp686A1668, DKFZp686O033, FH1, FLN1L, LRS1, SCT, TABP, TAP, filamin B , beta filamin, filamin 1 (actin-binding protein-280)-like, filamin B, beta (actin-binding protein-278). Official Symbol: FLNB. RefSeq number(s): NP_001448.2

Specificity: Human, Mouse, Rat, Dog 2602

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Preliminary experiments in Human Brain, Mouse Brain and Rat Brain lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Signaling, Cytoskeleton, Microfilaments

Restrictions: For Research Use only

Publications

Publications: Takafuta, Wu, Murphy et al.: "Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha." in: The Journal of biological chemistry, Vol. 273, Issue 28, pp. 17531-8, 1998 (PubMed).