CDCA7L antibody (C-Term)

Catalog No. ABIN1881189

This anti-CDCA7L antibody is a Rabbit Polyclonal antibody detecting CDCA7L in WB. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for CDCA7L antibody (C-Term) (ABIN1881189)

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA7L antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB43388

Product Details anti-CDCA7L Antibody

Binding Specificity: AA 290-317, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CDCA7L antibody (ABIN1881189)

Huang, Ho, Ponzielli, Barsyte-Lovejoy, Bouffet, Picard, Hawkins, Penn: "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells." in: Cancer research, Vol. 65, Issue 13, pp. 5607-19, (2005) (PubMed).

Chen, Ou, Chen, Choi, Shih: "R1, a novel repressor of the human monoamine oxidase A." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 11552-9, (2005) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Target Details for CDCA7L

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Alternative Name: CDCA7L

Background: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

UniProt: B3KTR5