CMIP antibody (C-Term)

Catalog No. ABIN1881214

This Rabbit Polyclonal antibody specifically detects CMIP in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for CMIP antibody (C-Term) (ABIN1881214)

Target: CMIP (C-Maf Inducing Protein (CMIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMIP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42683

Product Details anti-CMIP Antibody

Binding Specificity: AA 735-764, C-Term

Predicted Reactivity: M, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CMIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-764 amino acids from the C-terminal region of human CMIP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CMIP antibody (ABIN1881214)

Audard, Zhang, Copie-Bergman, Rucker-Martin, Ory, Candelier, Baia, Lang, Pawlak, Sahali: "Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes." in: Blood, Vol. 115, Issue 18, pp. 3756-62, (2010) (PubMed).

Kamal, Pawlak, BenMohamed, Valanciuté, Dahan, Candelier, Lang, Guellaën, Sahali: "C-mip interacts with the p85 subunit of PI3 kinase and exerts a dual effect on ERK signaling via the recruitment of Dip1 and DAP kinase." in: FEBS letters, Vol. 584, Issue 3, pp. 500-6, (2010) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for CMIP

Target: CMIP (C-Maf Inducing Protein (CMIP))

Alternative Name: CMIP

Background: CMIP plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.

Molecular Weight: 86331

NCBI Accession: NP_085132, NP_938204

UniProt: Q8IY22