ESCO1
(Establishment of Cohesion 1 Homolog 1 (ESCO1))
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
This ESCO1 antibody is un-conjugated
Application
Western Blotting (WB)
Clone
RB42857
Binding Specificity
AA 661-687, C-Term
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ESCO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-687 amino acids from the C-terminal region of human ESCO1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target
ESCO1
(Establishment of Cohesion 1 Homolog 1 (ESCO1))
Alternative Name
ESCO1
Background
Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.