Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179) antibody

Catalog No. ABIN1881724

This Rabbit Polyclonal antibody specifically detects in WB. It exhibits reactivity toward Human.

Quick Overview for Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179) antibody (ABIN1881724)

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Clone: RB40835

Product Details

Binding Specificity: AA 150-179

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAET1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the Central region of human RAET1E.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Alternative Name: RAET1E

Background: Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1, MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1, MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).

Molecular Weight: 30122

NCBI Accession: NP_001230254, NP_001230256, NP_001230257, NP_631904

UniProt: Q8TD07