UBE2K antibody (AA 109-139)

Catalog No. ABIN1882088

The Rabbit Polyclonal anti-UBE2K antibody has been validated for WB, IF and IHC (p). It is suitable to detect UBE2K in samples from Human and Mouse. There are 3+ publications available.

Quick Overview for UBE2K antibody (AA 109-139) (ABIN1882088)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4144

Product Details anti-UBE2K Antibody

Binding Specificity: AA 109-139

Predicted Reactivity: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-UBE2K antibody (ABIN1882088)

Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).

Kikuchi, Furukawa, Kubo, Tokura, Hayashi, Nakamura, Matsuda, Sakurabayashi: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).

Petersén, Mani, Brundin: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: HIP2

Background: HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.

Molecular Weight: 22407

NCBI Accession: NP_001104582, NP_001104583, NP_005330

UniProt: P61086