Arginine Vasopressin Receptor 1A (AVPR1A) antibody

Antigen: Arginine Vasopressin Receptor 1A (AVPR1A)

Synonyms: AVPR1, V1a, AVPR, V1aR, MGC108538, Avpr1, AVPR1A, MGC155312, VT4

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN190852

Additional Information

Alternative name: AVPR1A

Gene ID: 552, 54140 (mouse), 25107 (rat)

Immunogen: CHPLKTLQQPARRSR

Format: Affinity-purified

Description: All names and symbols: AVPR1A, arginine vasopressin receptor 1A, AVPR1 , SCCL vasopressin subtype 1a receptor, V1-vascular vasopressin receptor AVPR1A, V1a vasopressin receptor, antidiuretic hormone receptor 1A, vascular/hepatic-type arginine vasopressin receptor. Official Symbol: AVPR1A. RefSeq number(s): NP_000697.1

Specificity: Human, Mouse, Rat, Dog

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave an approx 90kDa band in Human and Rat Brain lysates after 0.03µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 46.8kDa according to NP_000697.1. The 90kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Yirmiya, Rosenberg, Levi et al.: "Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills." in: Molecular psychiatry, Vol. 11, Issue 5, pp. 488-94, 2006 (PubMed).