Zinc Finger, DHHC-Type Containing 8 (ZDHHC8) antibody

Antigen: Zinc Finger, DHHC-Type Containing 8 (ZDHHC8)

Synonyms: DHHC8, ZNF378, ZDHHCL1, ZDHHC8, znf378, zdhhcl1, zdhhc8

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN190853

Additional Information

Alternative name: ZDHHC8

Gene ID: 29801, 27801 (mouse), 303796 (rat)

Immunogen: C-QRDHPQLKTPPSK

Format: Affinity-purified

Description: All names and symbols: ZDHHC8, zinc finger, DHHC-type containing 8 , ZDHHCL1, ZNF378 , membrane-associated DHHC8 zinc finger protein, zinc finger, DHHC domain containing 8, zinc finger, DHHC domain like containing 1. Official Symbol: ZDHHC8. RefSeq number(s): NP_037505.1

Specificity: Human, Mouse, Rat, Dog

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 80-85kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 81.4kDa according to NP_037505.1). Recommended concentration: 1-3µg/ml. An additional band of

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Neurology, Transcription Factors, Amino Acids

Restrictions: For Research Use only

Images

ABIN190853 (0.1 ug/ml) staining of Human Brain (Frontal Cortex) lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Mukai, Liu, Burt et al.: "Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia." in: Nature genetics, Vol. 36, Issue 7, pp. 725-31, 2004 (PubMed).

Glaser, Schumacher, Williams et al.: "No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples." in: Biological psychiatry, Vol. 58, Issue 1, pp. 78-80, 2005 (PubMed).