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Antibodies
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anti-Myeloperoxidase (MPO) antibody
Myeloperoxidase (MPO) antibody
| Antigen |
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| Synonyms |
KIAA4033, mKIAA4033, mpo, fj80f04, wu:fj80f04, MPO, LOC100335032 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (24), ELISA (23), Enzyme Immunoassay (EIA) (18), Flow Cytometry (FACS) (17), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunoprecipitation (IP) (12), Immunohistochemistry (IHC) (6), Immunofluorescence (IF) (5), ELISA (Capture) (4), ELISA (Detection) (4), Immunocytochemistry (ICC) (1), Immunoelectrophoresis (IEP) (1)
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| Catalog no. |
ABIN191711 |
| Quantity |
20 µl (Variants) |
| Price |
195.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: MPO
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Alternative name
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Myeloperoxidase
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Swiss-Prot
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P05164
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Immunogen
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Human myeloperoxidase
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Cross-Reactivity
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Human
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Description
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Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils andsecreted during their activation. Native Myeloperoxidase is represented as a covalentlybound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and twounglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9. 2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophilcytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e. g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilicgranulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidaseautoantibody levels are also reported in rheumatoid arthritis. Recently it was shown thatMyeloperoxidase participates in the initiation and progression of cardiovascular disease. Itpossesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiacmarkers.
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Specificity
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This antibody detects myeloperoxidase. Species: Human. Others not tested.
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Application Notes
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ELISA. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Serum
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Buffer
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0,1M NaCl, 0,015M NaN3Reconstitution: Restore in aqua bidest to 1 mg/ml.
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Storage
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Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.
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Research Area
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Cancer, Innate Immunity, Enzymes, Metabolism, Immunology
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Restrictions
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For Research Use only
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Alternatives for antigen "Myeloperoxidase (MPO)", type "Antibodies"
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Hosts
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Mouse (48), Rabbit (38)
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Reactivities
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Human (76), Mouse (Murine) (4), Rat (Rattus) (4)
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Applications
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Western Blotting (WB) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (24), ELISA (23), Enzyme Immunoassay (EIA) (18), Flow Cytometry (FACS) (17), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunoprecipitation (IP) (12), Immunohistochemistry (IHC) (6), Immunofluorescence (IF) (5), ELISA (Capture) (4), ELISA (Detection) (4), Immunocytochemistry (ICC) (1), Immunoelectrophoresis (IEP) (1)
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Conjugates
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FITC (4), Biotin (1), PE (1), RPE (1)
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Epitopes
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C-Term (4), N-Term (2)
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