Sialoadhesin/CD169 antibody
Quick Overview for Sialoadhesin/CD169 antibody (ABIN206712)
Target
See all Sialoadhesin/CD169 (SIGLEC1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicuous property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
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Purification
- Protein A purified
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Immunogen
- Rat spleen cell homogenate.
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Isotype
- IgG2a
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anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (AA 851-950) antibody
SIGLEC1 Reactivity: Human, Rat FACS, ELISA, IHC (fro), ICC, IF (cc), IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (AA 20-197) antibodySIGLEC1 Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 2A4D1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibody (APC)SIGLEC1 Reactivity: Human FACS Host: Mouse Monoclonal 7-239 APC
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibodySIGLEC1 Reactivity: Rat FACS, IP, IHC (fro), IF Host: Mouse Monoclonal ED3 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibody (PE)SIGLEC1 Reactivity: Human FACS Host: Mouse Monoclonal 7-239 PE
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibodySIGLEC1 Reactivity: Human FACS, WB, IP, IHC (fro) Host: Mouse Monoclonal 7-239 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibodySIGLEC1 Reactivity: Mouse WB, IHC Host: Rat Monoclonal 3D6-112 unconjugated Recombinant Antibody
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (AA 851-950) antibody (AbBy Fluor® 647)SIGLEC1 Reactivity: Human, Rat FACS, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (N-Term) antibodySIGLEC1 Reactivity: Human FACS, WB, IHC, IF Host: Mouse Monoclonal HSn 7D2 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (Internal Region) antibodySIGLEC1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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Application Notes
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Approved: Flo (1:500), IHC, IHC-Fr (1:250), IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Comment
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
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Alternative Name
- SIGLEC1 / CD169 / Sialoadhesin
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Background
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Name/Gene ID: SIGLEC1
Family: Immunoglobulin
Synonyms: SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1 -
Gene ID
- 6614
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UniProt
- Q9BZZ2
Target
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