CCL2 antibody

Catalog No. ABIN208962

The Mouse Monoclonal anti-CCL2 antibody (ABIN208962) specifically detects CCL2 in WB, IHC, ELISA, IP, Neut and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CCL2 antibody (ABIN208962)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCL2 Antibody

Specificity: Reacts with both human natural and recombinant MCP-1 in ELISA. Inhibits the biological activity of natural and recombinant human MCP-1. No cross-reactivities with other cytokines have been detected.

Purification: Purified

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, IHC, IHC-Fr, IP, Neut, WB (1:10)

Usage: Suitable for use in ELISA, Immunoprecipitation, Western Blot and Neutralization of human MCP-1 in bio-assays. Furthermore the antibody can be used to stain cells containing MCP-1 in frozen sections as well as in cell cultured on cover slips. Immunohistology: 1:10. Western Blot: 1:10. For neutralization of biological activity dilutions have to be made according to the amounts of MCP-1 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: CCL2 / MCP-1

Background: Name/Gene ID: CCL2
Subfamily: Intercrine beta
Family: Intercrine

Synonyms: CCL2, C-C motif chemokine 2, Chemokine (C-C motif) ligand 2, GDCF-2, HC11, HSMCR30, MCP1, SCYA2, Small-inducible cytokine A2, Monocyte secretory protein JE, MCAF, MCP-1, Monocyte chemotactic protein 1, SMC-CF

Gene ID: 6347

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection