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Integrin Alpha2b antibody

CD41 Reactivity: Human FACS Host: Mouse Monoclonal unconjugated

Catalog No. ABIN209281

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Reactivity
148

31

21

8

7

5

3

3

2

2

2

1

1

1

1

1
Human
Host
101

48

22

1
Mouse
Compatible Secondaries
Clonality
122

44

1
Monoclonal
Conjugate
65

18

14

13

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is un-conjugated
Application
127

45

30

26

22

21

13

13

10

9

8

5

2

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone 3H1299 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex. Species cross-reactivity: Clone 3H1299 is reported to cross-react with baboon.

Purification

Protein G purified

Immunogen

Human platelet plasma membrane.

Type of Immunogen: Membrane preparation

Isotype

IgG1

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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated

Application Notes

Approved: Flo

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL human whole blood. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Purified IgG - liquid

Preservative

Azide free

Handling Advice

Avoid repeat freeze-thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Target

Integrin Alpha2b (CD41)

Alternative Name

ITGA2B / CD41 (CD41 Products)

Background

Name/Gene ID: ITGA2B
Family: Integrin

Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA

Gene ID

3674

UniProt

P08514

Pathways

Integrin Complex