CD137 antibody

Catalog No. ABIN7470757

This Rat Monoclonal antibody specifically detects CD137 in ELISA and FACS. It exhibits reactivity toward Human and Cynomolgus.

Quick Overview for CD137 antibody (ABIN7470757)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Human, Cynomolgus

Host: Rat

Clonality: Monoclonal

Conjugate: This CD137 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: JG1-6A

Product Details anti-CD137 Antibody

Specificity: Recognizes human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 Molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumor necrosis receptor family and is reported to regulate T-cell activation and proliferation.

Purification: Protein G purified

Immunogen: Recombinant human CD137-Fc.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, Flo

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris buffered saline, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: TNFRSF9 / 4-1BB / CD137

Background: Name/Gene ID: TNFRSF9
Family: TNF Receptor

Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137

Gene ID: 3604

UniProt: Q07011

Pathways: Cancer Immune Checkpoints