CD11c antibody (PE)

Catalog No. ABIN219423

Product Details anti-CD11c Antibody (PE)

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivity: Human, Monkey, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11c antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Recognizes the integrin alpha-x subunit, a 150kD glycoprotein expressed by macrophages, monocytes, granulocytes and NK cells. The antigen is also expressed by hairy cell leukaemia cells. Ligands for CD11c are ICAM-1, iC3b and fibrinogen. The molecule has a role in mediating adherence of granulocytes and monocytes to endothelium and fibrinogen. Species cross-reactivity: Clone 3H984 is reported to cross-react with Cynomolgus monkey and canine.

Purification: Purified

Immunogen:

Type of Immunogen: Native protein

Clone: BU15

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Alternative Name: ITGAX / CD11c (ITGAX Products)

Background: Name/Gene ID: ITGAX
Family: Integrin

Synonyms: ITGAX, CD11c antigen, Integrin alpha-X, Leu M5, alpha subunit, p150 95 integrin alpha chain, SLEB6, CD11C, Leu M5

Gene ID: 3687

UniProt: P20702

Pathways: Complement System, Activated T Cell Proliferation, Integrin Complex