CD11c Products
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Categories
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq, Jul 2008].
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Featured CD11c Categories
CD11c Antibodies
High quality antibodies with extensive validation data.
CD11c Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD11c Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
FACS
Validations
- (5)
- (4)
Cat. No.
ABIN302018
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IF, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN390974
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, WB, IF
Validations
- (5)
Cat. No.
ABIN7249394
Quantity
200 μL
Datasheet
Datasheet
Recommended CD11c ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6226842
Quantity
96 tests
Datasheet
Datasheet
Recommended CD11c Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123475
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308185
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3093196
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CD11c products
: "MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB." in: JCI insight, Vol. 5, Issue 8, (2021) (PubMed).: "In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice." in: Stem cell research & therapy, Vol. 12, Issue 1, pp. 408, (2021) (PubMed).
: "Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice." in: International immunopharmacology, Vol. 88, pp. 106945, (2021) (PubMed).
: "Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 7, pp. 8634-8647, (2019) (PubMed).
: "Mitochondria elongation is mediated through SIRT1-mediated MFN1 stabilization." in: Cellular signalling, Vol. 38, pp. 67-75, (2018) (PubMed).
: "Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy." in: Cancer cell, Vol. 34, Issue 4, pp. 561-578.e6, (2018) (PubMed).
: "Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity." in: Scientific reports, Vol. 7, Issue 1, pp. 2707, (2017) (PubMed).
: "A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease." in: Cell, Vol. 169, Issue 7, pp. 1276-1290.e17, (2017) (PubMed).
: "DCs facilitate B cell responses against microbial DNA via DC-SIGN." in: PLoS ONE, Vol. 12, Issue 10, pp. e0185580, (2017) (PubMed).
: "CD137 Stimulation Enhances Cetuximab-Induced Natural Killer: Dendritic Cell Priming of Antitumor T-Cell Immunity in Patients with Head and Neck Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 3, pp. 707-716, (2016) (PubMed).
Synonyms and alternative names related to CD11c
integrin subunit alpha X (ITGAX), integrin subunit alpha X (Itgax), integrin alpha X (Itgax), AI449405, CD11C, Cd11c, Cr4, N418, RGD1561123, SLEB6Protein level used designations for CD11c
- CD11 antigen-like family member C
- integrin alpha-X
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- leu M5, alpha subunit
- leukocyte adhesion glycoprotein p150,95 alpha chain
- leukocyte adhesion receptor p150,95
- leukocyte surface antigen p150,95, alpha subunit
- myeloid membrane antigen, alpha subunit
- p150 95 integrin alpha chain
- CD11C (p150) alpha polypeptide
- complement receptor 4
- integrin aX
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