CD24 Molecule (CD24) antibody
| Antigen |
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| Synonyms |
HSA, Cd24, Ly-52, nectadrin, CD24A, FLJ22950, FLJ43543, MGC75043 |
| Clonality |
Monoclonal (SN3) |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
Flow Cytometry (FACS) (161), Immunohistochemistry (Frozen Sections) (IHC (fro)) (45), Immunofluorescence (IF) (24), Western Blotting (WB) (22), Immunoprecipitation (IP) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunohistochemistry (IHC) (8), ELISA (4), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN238502 |
| Quantity |
0.1 mg (Variants) |
| Price |
270.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen
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Alternative name
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CD24
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Swiss-Prot
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P25063
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Immunogen
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Glycoproteins purified from human NALM-1 cell line.
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Cross-Reactivity
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Human
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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SN3
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Description
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CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-likeGPI-anchored extracellular membrane glycoprotein expressed on several cell types,including B cells. When B cells are activated and induced to further maturation, however,CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, therebyregulating the activity of integrins and other proteins such as the chemokine receptorCXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cellprecursors but not in mature resting B cells, where it instead inhibits their ability toproliferate in response to activation. CD24 expression is associated with invasiveness andpoorer prognosis of carcinomas and is a marker of exosomes secreted into urine andamniotic fluid.
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Specificity
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The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cellmalignancies. It is not expressed on human thymocytes. Species: Human. Others not tested.
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Application Notes
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Suitable for Flow Cytometry and Immunohistochemistry (frozen sections). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Aff - Purified
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Buffer
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PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Storage
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Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Research Area
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CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "CD24 Molecule (CD24)", type "Antibodies"
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Hosts
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Mouse (76), Rat (72), Rabbit (24)
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Reactivities
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Human (97), Mouse (Murine) (92), Rat (Rattus) (21), Cow (Bovine) (1), Horse (Equine) (1), Pig (Porcine) (1), Sheep (Ovine) (1)
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Applications
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Flow Cytometry (FACS) (161), Immunohistochemistry (Frozen Sections) (IHC (fro)) (45), Immunofluorescence (IF) (24), Western Blotting (WB) (22), Immunoprecipitation (IP) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunohistochemistry (IHC) (8), ELISA (4), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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FITC (27), PE (21), Biotin (14), Cy5,PE (4), APC (3), Cy5.5 (3), RPE (3), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), Pacific Blue (1), RBITC (1)
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