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Thyroid Stimulating Hormone, beta (TSHB) antibody

Antigen

Thyroid Stimulating Hormone, beta (TSHB)

Synonyms CHNG4, TSH-BETA
Clonality Monoclonal (TSH-116)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)
Catalog no. ABIN238514
Quantity 0.1 mg  (1.0 mg/ml)
Price 245.00 $   Plus shipping costs $35.00
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Additional Information

Characteristics Synonyms: hTSH, Thyroid-stimulating hormone
Alternative name Thyrotropin beta chain
Immunogen Human thyrotropin.
Cross-Reactivity Human
Isotype IgG2a  (Matching secondary antibodies)
Clone TSH-116
Description Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates itto produce more thyroid hormones. hTSH is composed of two subunits - alpha and beta.
Specificity The antibody TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin),a glycoprotein hormone produced by the anterior pituitary gland cells in response tosignals from the hypothalamus gland in the brain. The TSH-116 reacts with association constant 1. 1 x 1011 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) wasdetermined by solid phase RIA with excess of the antibody TSH-116: hTSH (78. 9), hCG(20. 3), hLH (23. 2), hFSH (29. 9). Species: Human. Others not tested.

Application Details

Application Notes ELISA. RIA. The antibody TSH-116 is suitable in combination with the antibody TSH-51 (ABIN238515)for Immunometric assays in the screening of neonatal hypothyroidism. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS, pH 7.4 with 15 mM sodium azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Hormones
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Thyroid Stimulating Hormone, beta (TSHB)", type "Antibodies"
Hosts Mouse (38), Rabbit (7), Goat (2), Sheep (1)
Reactivities Human (44), Cow (Bovine) (1), Dog (Canine) (1), Mouse (Murine) (1), Rat (Rattus) (1)
Applications Enzyme Immunoassay (EIA) (30), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Western Blotting (WB) (6), ELISA (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), ELISA (Capture) (3), ELISA (Detection) (3), Immunofluorescence (IF) (3), Radioimmunoassay (RIA) (3), Conjugation (1), ELISA Pair (1)
Conjugates HRP (5)
Epitopes intact (4), Center (1)