Hornerin (HRNR) antibody

Antigen: Hornerin (HRNR)

Synonyms: S100A16, S100a18, AV011854, S100a18-ps1, 1110033K19Rik, A530063N20Rik

Clonality: Polyclonal

Host: Goat

Reactivity: Please enquire

Conjugate: Un-conjugated

Application: ELISA

Catalog no.: ABIN238644

Additional Information

Alternative name: Hornerin

Gene ID: 388697

Immunogen: C-QYATQHGEYDTLNK

Description: All names and symbols: HRNR, hornerin, S100A16, S100a18, intermediate filament-associated protein. Official Symbol: HRNR . RefSeq number(s): NP_001009931.1

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Preliminary experiments gave an approx 50kDa band in Human Skin lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 282kDa according to NP_001009931.1. The 50kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Cytoskeleton

Restrictions: For Research Use only

Publications

Wang, Wang, Cao et al.: "Hornerin gene was involved in a case of acute myeloid leukemia transformed from myelodysplastic syndrome with t(1;2)(q21;q37)." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 20, Issue 12, pp. 2184-7, 2006 (PubMed).