TRPM4 antibody

Catalog No. ABIN2725815

This anti-TRPM4 antibody is a Mouse Monoclonal antibody detecting TRPM4 in WB and IHC. Suitable for Human, Dog and Monkey. This Primary Antibody has been cited in 10+ publications.

Quick Overview for TRPM4 antibody (ABIN2725815)

Target: TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))

Reactivity: Human, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRPM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 10H5

Product Details anti-TRPM4 Antibody

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human TRPM4 (NP_060106) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:5000~10000, IHC 1:50,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-TRPM4 antibody (ABIN2725815)

Riquelme, Silva, Philp, Huidobro-Toro, Cerda, Trimmer, Leiva-Salcedo: "Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3." in: Frontiers in cellular neuroscience, Vol. 12, pp. 12, (2018) (PubMed).

Sarmiento, Montorfano, Cerda, Cáceres, Becerra, Cabello-Verrugio, Elorza, Riedel, Tapia, Velásquez, Varela, Simon: "Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel." in: Microvascular research, Vol. 98, pp. 187-96, (2015) (PubMed).

Inoue, Hur, Kihara, Teranishi, Yamamoto, Ishikawa, Wiehager, Winblad, Tjernberg, Schedin-Weiss: "Human brain proteins showing neuron-specific interactions with ?-secretase." in: The FEBS journal, Vol. 282, Issue 14, pp. 2587-99, (2015) (PubMed).

Wang, Cheng, Liu, Zhang, Li, Li: "CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer." in: Cellular signalling, Vol. 27, Issue 7, pp. 1369-79, (2015) (PubMed).

Elhammali, Ippolito, Collins, Crowley, Marasa, Piwnica-Worms: "A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor." in: Cancer discovery, Vol. 4, Issue 7, pp. 828-39, (2014) (PubMed).

Qiang, Xiao, Su, Wu, Tong, Liu, He: "A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse." in: Journal of Alzheimer's disease : JAD, Vol. 40, Issue 4, pp. 1039-53, (2014) (PubMed).

Maleszewski, Larsen, Kip, Castonguay, Edwards, Carney, Kipp: "PRKAR1A in the development of cardiac myxoma: a study of 110 cases including isolated and syndromic tumors." in: The American journal of surgical pathology, Vol. 38, Issue 8, pp. 1079-87, (2014) (PubMed).

Muniz, Egloff, Kiss: "RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP." in: Nucleic acids research, Vol. 41, Issue 8, pp. 4686-98, (2013) (PubMed).

Becerra, Echeverría, Varela, Sarmiento, Armisén, Nuñez-Villena, Montecinos, Simon: "Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death." in: Cardiovascular research, Vol. 91, Issue 4, pp. 677-84, (2011) (PubMed).

Tong, Boileau, Furukawa, Chang, Wilson, Houle, Kish: "Distribution of vesicular monoamine transporter 2 protein in human brain: implications for brain imaging studies." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 31, Issue 10, pp. 2065-75, (2011) (PubMed).

Target Details for TRPM4

Target: TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))

Alternative Name: TRPM4

Molecular Weight: 134.3 kDa

Gene ID: 54795

NCBI Accession: NM_017636

HGNC: 54795

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response