ST8SIA1 antibody (N-Term)

Catalog No. ABIN2505957

The Rabbit Polyclonal anti-ST8SIA1 antibody has been validated for WB. It is suitable to detect ST8SIA1 in samples from Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit and Rat.

Quick Overview for ST8SIA1 antibody (N-Term) (ABIN2505957)

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST8SIA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ST8SIA1 Antibody

Binding Specificity: N-Term

Sequence: GSFYTHSPLT IQLTLSSHRC NLPPLSSEYT KDVGSKSQLV TANPSIIRQR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ST8SIA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human ST8SIA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ST8SIA1

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Alternative Name: ST8SIA1

Background: Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: GD3S, SIAT8, SIAT8A, SIAT8-A, ST8SiaI
Protein Size: 213

Molecular Weight: 23 kDa

Gene ID: 6489

NCBI Accession: NM_001304450, NP_001291379

UniProt: Q92185