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CD44 antibody (violetFluor™ 450)

CD44 Reactivity: Human, Mouse FACS Host: Rat Monoclonal IM7 violetFluor™ 450

Catalog No. ABIN2567703

Datasheet as PDF

Target See all CD44 Antibodies

CD44
Reactivity
280

137

71

31

25

23

14

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1

1
Human, Mouse
Host
166

118

74

1

1
Rat
Compatible Secondaries
Clonality
249

109

2
Monoclonal
Conjugate
163

41

30

22

16

7

6

5

5

5

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This CD44 antibody is conjugated to violetFluor™ 450
Application
265

146

84

71

70

65

54

41

40

30

26

15

7

6

5

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24).

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

IM7

Isotype

IgG2b kappa

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CD44 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD44

Alternative Name

CD44 (CD44 Products)

Background

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Gene ID

960, 12505

UniProt

P16070, P15379

Pathways

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling