Integrin beta 3 antibody
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- Target See all Integrin beta 3 (ITGB3) Antibodies
- Integrin beta 3 (ITGB3)
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Reactivity
- Mouse, Rat
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This Integrin beta 3 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 Molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Clone
- 2C9-G3
- Isotype
- IgG
- Top Product
- Discover our top product ITGB3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- Integrin beta 3 (ITGB3)
- Alternative Name
- CD61 (ITGB3 Products)
- Background
- The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 Molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51. The complex binds to other ligands such as fibrinogen, fibronectin, thrombospondin, and von WIllebrand factor. It is expressed by granulocytes, platelets, activated T cells, smooth muscle, and a subset of B cells.
- Gene ID
- 16416
- UniProt
- O54890
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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